Institute of Biochemistry
Publications 2014

Lin J, Eggensperger S, Hank S, Wycisk A, Wieneke R, Mayerhofer PU, Tampé R
A negative feedbackmodulator of antigen processing evolved from a frameshift in the cowpox virus genome.
PLoS Pathog. 2014 Dec 11,DOI: 10.1371/journal.ppat.1004554

Grossmann N, Vakkasoglu AS, Hulpke S, Abele R, Gaudet R, Tampé R.
Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter.
Nat Commun. 2014 Nov 7;5:5419. doi: 10.1038/ncomms6419.

Kim J, Wu S, Tomasiak TM, Mergel C, Winter MB, Stiller SB, Robles-Colmanares Y, Stroud RM, Tampé R, Craik CS, Cheng Y.
Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter.
Nature. 2014 Nov 2. doi: 10.1038/nature13872.

Hinz A, Jedamzick J, Herbring V, Fischbach H, Hartmann J, Parcej D, Koch J, Tampé R.
Assembly and function of the MHC I peptide-loading complex are conserved across higher vertebrates
J. Biol. Chem. 2014 Oct 15; 289: 33109-33117.

Eggensperger S, Fisette O, Parcej D, Schäfer LV, Tampé R.
An annular lipid belt is essential for allosteric coupling and viral inhibition of the antigen translocation complex TAP.
J. Biol. Chem. 2014; 289: 33098-33108.

Wieneke R, Laboria N , Rajan M, Kollmannsperger A, Natale F, Cardoso MC , Tampé R.
Live-cell targeting of His-tagged proteins by multivalent N-nitrilotriacetic acid carrier complexes
J. Am. Chem. Soc., 2014, 136 (40), pp 13975–13978 DOI: 10.1021/ja5063357.

Mayerhofer PU, Tampé R.
Antigen Translocation Machineries in Adaptive Immunity and Viral Immune Evasion.
Mol Biol. 2014 Sep 12. pii: S0022-2836(14)00493-8. doi: 10.1016/j.jmb.2014.09.006.

Nair-Gupta P, Baccarini A, Tung N, Seyffer F, Florey O, Huang Y, Banerjee M, Overholtzer M, Roche PA, Tampé R, Brown BD, Amsen D, Whiteheart SW, Blander JM.
TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation
Cell. 2014 July 31;158(6):506–21. doi: 10.1016/j.cell.2014.04.054

Seyffer F, Tampé R.
ABC transporters in adaptive immunity.
Biochim Biophys Acta. 2014 Jun 9. pii: S0304-4165(14)00220-7. doi: 10.1016/j.bbagen.2014.05.022.

Arnold P, Himmels P, Weiß S, Decker TM, Markl J, Gatterdam V, Tampé R, Bartholomäus P, Dietrich U, Dürr R1.
Antigenic and 3D structural characterization of soluble X4 and hybrid X4-R5 HIV-1 Env trimers.
Retrovirology. 2014 May 30;11(1):42. doi: 10.1186/1742-4690-11-42.

Gatterdam V, Ramadass R, Stoess T, Fichte MA, Wachtveitl J, Heckel A, Tampé R.
Three-Dimensional Protein Networks Assembled by Two-Photon Activation.
Angew Chem Int Ed Engl. 2014 May ;53(22):5680-84.

Gatterdam V1, Ramadass R, Stoess T, Fichte MA, Wachtveitl J, Heckel A, Tampé R.
Dreidimensionale Proteinnetzwerke durch Zwei-Photonen-Aktivierung
Angew Chem 2014 May 126(22):5787-91.

Urban M, Kleefen A, Mukherjee N, Seelheim P, Windschiegl B, von der Brüggen M, Kocer A, Tampé R.
Highly parallel transport recordings on a membraneon-nanopore chip at single molecule resolution.
Nano Lett. 2014 Mar 12;14(3):1674-80. doi: 10.1021/nl5002873. Epub 2014 Feb 17.

Publications 2013

Pollheimer P, Taskinen B, Scherfler A, Gusenkov S, Creus M, Wiesauer P, Zauner D, Schöfberger W, Schwarzinger C, Ebner A, Tampé R, Stutz EH, Hytonen VP, Gruber HJ.
Reversible biofunctionalization of surfaces with a switchable mutant of avidin.
Bioconjug Chem. 2013 Oct 16;24(10):1656-68.

Tumulka F, Roos C, Löhr F, Bock C, Bernhard F, Dötsch V, Abele R.
Conformational stabilization of the membrane embedded targeting domain of the lysosomal peptide transporter TAPL for solution NMR.
J Biomol NMR. 2013 Oct;57(2):141-54.

Rangl M, Ebner A, Yamada J, Rankl C, Tampe R, Gruber HJ, Rexach M, Hinterdorfer P.
Single-Molecule Analysis of the Recognition Forces Underlying
Nucleo-Cytoplasmic Transport

Angew Chem Int Ed Engl. 2013 Sep 23;52(39):10356-9.

Baldauf C, Schulze K, Lueders P, Bordignon E, Tampé R.
In-Situ Spin Labeling of His-Tagged Proteins: Distance Measurements under In-Cell Conditions.
Chemistry. 2013 Oct 4;19(41):13714-9.

Hulpke S, Tampé R.
The MHC I loading complex: a multitasking machinery in adaptive immunity.
Trends Biochem Sci. 2013 Aug;38(8):412-20.

Parcej D, Guntrum R, Schmidt S, Hinz A, Tampé R.
Multicolour Fluorescence-Detection Size-Exclusion Chromatography for Structural Genomics of Membrane Multiprotein Complexe
PLoS One. 2013 Jun 25;8(6):e67112.

Nürenberg E, Tampé R.
Tying up loose ends: ribosome recycling in eukaryotes and archaea.
Trends Biochem Sci. 2013 Feb;38(2):64-74.

Labòria N, Wieneke R, Tampé R.
Control of nanomolar interaction and in situ assembly of proteins in four dimensions by light.
Angew Chem Int Ed Engl. 2013 Jan 14;52(3):848-53.