Please contact:

Dr. Inga Hänelt
Junior Professor
Biocenter N220/1.03
phone +49-69-798 29 261


All publications

Diskowski M, Mehdipour AR, Wunnicke D, Mills DJ, Mikusevic V, Bärland N, Hoffmann J, Morgner N, Steinhoff HJ, Hummer G, Vonck J#, Hänelt I#.
Helical jackknives control the gates of the double-pore K+ uptake system KtrAB.

eLife (2017), advanced online.

Wunnicke D, Hänelt I.
The synergetic effects of combining structural biology and EPR apectroscopy on membrane proteins.
Crystals (2017) 7, 117.

Hänelt I*, Jensen S*, Wunnicke D, Slotboom DJ.
Low affinity and slow Na+ binding precedes high affinity aspartate binding in GltPh.
J. Biol. Chem. (2015) 290, 15962-15972.

Diskowski M, Mikusevic V, Stock C, Hänelt I.
Functional diversity of the superfamily of K+ transporters to meet various requirements.
Biol. Chem. (2015) 396, 1003-1014.

Shiyan A, Thompson M, Köcher S, Tausendschön M, Santos H, Hänelt I, Müller V.
Glutamine synthetase 2 is not essential for biosynthesis of compatible solutes in Halobacillus halophilus.

Front. Microbiol. (2014), doi: 10.3389/fmicb.2014.00168.

Erkens GB, Hänelt I, Goudsmits JMH, Slotboom DJ, van Oijen AM.
Unsynchronised subunit motion in single trimeric Na(+)-coupled aspartate transporters.
Nature (2013) 502, 119-123.

Jensen S, Guskov A, Rempel S, Hänelt I, Slotboom DJ. 
Crystal structure of a substrate-free aspartate transporter.
Nat. Struct. Mol. Biol. (2013) 20, 1224-1226.
Highlighted by: Kanner BI. Substrate-induced rearrangements in glutamate-transporter homologs. Nat. Struct. Mol. Biol. (2013) 20, 1142-1144.

Majsnerowska M*, Hänelt I*, Wunnicke D*, Schäfer LV, Steinhoff HJ, Slotboom DJ. 
Mechanism of substrate binding to the S-component ThiT from an ECF-type ABC transporter.
Structure (2013) 21, 861-867.

Hänelt I, Wunnicke D, Bordignon E, Steinhoff HJ, Slotboom DJ. 
Conformational heterogeneity of the aspartate transporter Glt(Ph).
Nat. Struct. Mol. Biol. (2013) 20, 210-214.

Pade N, Köcher S, Roeßler M, Hänelt I, Müller V. 
Bioenergetics of the moderately halophilic bacterium Halobacillus halophilus: Composition and regulation of the respiratory chain.
Appl. Environ. Microbiol. (2013) 79, 3839-3846.

Mesbah NM, Hänelt I, Zhao B, Müller V.
Microbial adaptation to saline environments: Lessons from the genomes of Natranaerobius thermophilus and Halobacillus halophilus.
In: Genetics and Genomics of Halophiles (2013) (Papke, R.T., Oren, A., eds.).

Hänelt I, Müller V.
Molecular Mechanisms of Adaptation of the Moderately Halophilic Bacterium Halobacillis halophilus to Its Environment.
Life (2013) 3, 234-243.

Hänelt I#, Tholema N, Kröning N, Vor der Brüggen M, Wunnicke D, Bakker EP.
KtrB, a member of the superfamily of K(+) transporters.
Eur. J. Cell Biol. (2011) 90, 696-704.

Hänelt I*#, Wunnicke D*, Müller-Trimbusch M, Vor der Brüggen M, Kraus I, Bakker EP, Steinhoff HJ.
Membrane region M(2C2) in subunit KtrB of the K(+) uptake system KtrAB from Vibrio alginolyticus forms a flexible gate controlling K(+) flux; an electron paramagnetic resonance study.
J. Biol. Chem. (2010) 285, 28210-28219.

Hänelt I#, Löchte S, Sundermann L, Elbers K, Vor der Brüggen M, Bakker EP.
Gain of function mutations in membrane region M(2C2) of KtrB open a gate controlling K(+) transport by the KtrAB system from Vibrio alginolyticus.
J. Biol. Chem. (2010) 285, 10318-10327.

Kröning N, Willenborg M, Tholema N, Hänelt I, Schmid R, Bakker EP.
ATP binding to the KTN/RCK subunit KtrA from the K(+) uptake system KtrAB of Vibrio alginolyticus: its role in the formation of the KtrAB complex and its requirement in vivo.
J. Biol. Chem. (2007) 282, 14018-27.

*authors contibuted equally
#corresponding author