Group Members

Dr. Alexander Gottschalk
Professor & Group Leader     
phone +49-(0)69-798-42518 fax +49-(0)69-798-763-42518

Dr. Jana Liewald        
Postdoctoral Fellow
phone +49-(0)69-798-42513


Dr. Christina Schüler      
Postdoctoral Fellow
phone +49-(0)69-798-42520

Dr. Holger Dill    
Postdoctoral Fellow
phone +49-(0)69-798-42519
dill@biochem.uni-frankfurt.de

Barbara Jánosi       
PhD Student    
phone +49-(0)69-798-42519
Janosi@em.uni-frankfurt.de

Jonas Weil     
PhD Student
phone +49-(0)69-798-42713
weil@biochem.uni-frankfurt.de 

Frank Becker     
PhD Student
phone +49-(0)69-798-42519
fr.becker@em.uni-frankfurt.de

Thilo Henß     
PhD Student
phone +49-(0)69-798-42519
Henss@biochem.uni-frankfurt.de

Marcial Engel    
PhD Student
phone +49-(0)69-798-42713
marcial.engel@biochem.uni-frankfurt.de

Maximilian Bach    
PhD Student
phone +49-(0)69-798-42519
Bach@bpc.uni-frankfurt.de

Amelie Bergs   
PhD Student
phone +49-(0)69-798-42713
amelie.bergs@stud.uni-frankfurt.de

Martin Schneider   
PhD Student
phone +49-(0)69-798-42519
martinw.schneider@stud.uni-frankfurt.de

Publications 2016

 

Safdie G, Liewald JF, Kagan S, Battat E, Gottschalk A, Treinin M. (2016) RIC-3 phosphorylation enables dual regulation of excitation and inhibition of C. elegans muscle. Mol. Biol. Cell 27:2994-3003.

 

Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee J-S, Gottschalk A, Brose N, Schultz C, Trauner D. (2016) Photoswitchable diacylglycerols enable optical control of protein kinase C. Nature Chemical Biology 12: 755-62

Publications 2015

Schüler C*, Fischer E*, Shaltiel L, Steuer Costa W, Gottschalk A. (2015) Arrhythmogenic effects of mutated L-type Ca2+-channels on an optogenetically paced muscular pump in Caenorhabditis elegans. Scientific Reports 5:14427 | DOI: 10.1038/srep14427. PDF

Glock C, Nagpal J, Gottschalk A (2015) Microbial Rhodopsin Optogenetic Tools: Application for Analyses of Synaptic Transmission and of Neuronal Network Activity in Behavior. In: C. elegans: Methods and Applications, Methods in Molecular Biology (Biron D, Haspel G, eds.), vol. 1327, DOI 10.1007/978-1-4939-2842-2_8. 

Gao S#, Nagpal J#, Schneider M, Kozjak-Pavlovic J, Nagel G*, Gottschalk A*. (2015) Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp. Nature Communications 6: 8046. PDF

Hermann A, Liewald JF, Gottschalk A. (2015) A photosensitive degron enables acute light-induced protein degradation in the nervous system. Current Biology 25: R733–R752

Wabnig S, Liewald JF, Yu S-c, Gottschalk A (2015) High-throughput all-optical analysis of synaptic transmission and synaptic vesicle recycling in Caenorhabditis elegans. PLOS ONE 10(8): e0135584. doi:10.1371/journal.pone.0135584 PDF

Damijonaitis A, Broichhagen J, Urushima T, Hüll K, Nagpal J, Laprell L, Schönberger M, Woodmansee DH, Rafiq A, Sumser MP, Kummer W, Gottschalk A, Trauner D. (2015 Mar 5) AzoCholine enables optical control of alpha 7 nicotinic acetylcholine receptors in neural networks. ACS Chem Neurosci. 2015 May 20;6(5):701-7. doi: 10.1021/acschemneuro.5b00030. Epub 2015 Mar 27.

Butler VJ, Branicky R, Yemini E, Liewald JF, Gottschalk A, Kerr RA, Chklovskii DB, Schafer WR. (2015 Jan 6) A consistent muscle activation strategy underlies crawling and swimming in Caenorhabditis elegans. J. R. Soc. Interface 12(102)

Publications 2014

Steuer Costa W, Liewald JF, Gottschalk A. (2014) Photoactivated Adenylyl Cyclases as Optogenetic Modulators of Neuronal Activity. in: Photswitching Proteins (Sidney Cambridge, Editor). Springer Protocols. Methods in Molecular Biology 1148, p. 161-75

Cohen E, Chatzigeorgiou M, Husson SJ, Steuer Costa W, Gottschalk A, Schafer WR, Treinin M. (2014) C. elegans nicotinic acetylcholine receptors are required for nociception. Molecular and Cellular Neuroscience 59C: 85-96

AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A*, Liewald J*. (2014) Synthetic retinal analogs modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools. Nat. Communic. 5: 5810

Gottschalk A. (2014) Optogenetische Analyse der Funktion neuronaler Netzwerke und der synaptischen Transmission in Caenorhabditis elegans. Neuroforum 4/2014: 278-286

Gottschalk A. (2014) Optogenetic analyses of neuronal network function and synaptic transmission in Caenorhabditis elegans. e-Neuroforum 5: 77-85